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Developmental Immunotoxicology
- Dr Steven D. Holladay (Virginia Tech, Blacksburg, VA, USA)
- Pub Date
- November 2004
- Pages
- 384
- Size
- 6.125 x 9.25
- ISBN
- 9780415284578, 0415284570
Developmental Immunotoxicology explores immune system development in experimental animal and human models, and discusses complex issues related to the evolution of developmental immunology and risk assessment.
Using a didactic approach, this text describes models used to study developmental immunotoxicology and examples of specific developmental immunotoxic agents, including therapeutics. The text includes several chapters that describe the role of neuroimmune interactions as they relate to developmental immunotoxicology.
This guide covers:
• adverse postnatal consequences of perinatal immunotoxicological exposure
• different classes of developmental immunotoxicants such as halogenated and polycyclic aromatic hydrocarbons, pesticides, and heavy metals
• immune defects caused by immunotoxic compound exposure during development
• consequences of immune dysregulation (i.e. autoimmune and allergic disease) following developmental exposures
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