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Developmental Toxicology, Third Edition
Series: Target Organ Toxicology
- Dr Deborah K. Hansen (National Center for Toxicology Research, Jefferson, AR, US)
- Dr Barbara D. Abbott (US EPA, Research Triangle Park, NC, US)
- Pub Date
- October 2008
- Edition
- Third
- Series
- Target Organ Toxicology Series
- Volume
- 27
- Pages
- 496
- Size
- 6 x 9
- ISBN
- 9781420054378, 9781420054378
This text reviews the basic science, and clinical, epidemiological, and regulatory perspectives of developmental toxicology, and covers advances in genetics, biochemistry, molecular embryology, and cell biology.
Covering mathematical and statistical techniques and effects of toxic exposure on organ development, it examines pharmaceutical and environmental agent testing and data interpretation. The relationship between maternal and developmental toxicology and current techniques for studying chemical disposition, metabolism, and placental transfer are discussed.
Other topics:
• genetic factors in developmental toxicology
• regulatory aspects of testing and risk assessment
• pre- and postconceptional clinical care
• apoptosis and signal transduction pathways in normal and abnormal development
• epigenetic changes in development
• nutrition and individual susceptibility
• bioinformatics
• global and targeted gene expression changes
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